Ariana Boswell

All articles by Ariana Boswell

• Severe anti-Kell HDFN less likely in those with lower antibody levels

  A recent study found that an anti-Kell antibody level of eight can be used to reliably identify patients at risk of severe HDFN.

• Genetic and blood tests can improve detection of ABO-HDFN

  Integrating genetic data with immunological and blood testing can improve detection of HDFN due to ABO incompatibility, a study found.

• Researchers find new genetic variant that may be linked to HDFN

  A recent study found two patients with a novel mutation in the RHCE gene, which codes for several antigens found on red blood cells.

• J&J publishes easy to understand summary of nipocalimab trial

  The summary describes the design of Johnson & Johnson’s Phase 3 AZALEA trial, which will evaluate the efficacy of nipocalimab in HDFN.

• Pre-hospital blood transfusion program in California reduced HDFN mortality

  A blood transfusion protocol used in Los Angeles results in fewer deaths due to HDFN than other protocols.

• Targeted RhD immune globulin approach can help current shortage

  The United States is experiencing a shortage of RhD immune globulin, indicating a need for novel strategies to prevent HDFN.

• Case report: Rare RhD antigen variant found in patient

  A recent case report describes a 63-year-old woman in China who was diagnosed with a rare variant of the RhD antigen.

• Review: Global disparities in HDFN mortality persist

  A study identified several societal factors contributing to the disparity in infant mortality due to HDFN and other hemolytic disorders.

• New study to assess potential indicator of HDFN recruiting patients

  A new observational study in China aims to evaluate the utility of neonatal carbon monoxide concentrations in diagnosing and treating HDFN.

• Rare Disease Day: Why it matters and how to get involved

  Rare Disease Day 2025 aims to uplift the rare disease community and promote greater awareness.