Leonardo Jaimes, MD

All articles by Leonardo Jaimes, MD

• Study highlights lack of standardization in intrauterine transfusions

  Intrauterine transfusions are a fundamental treatment of anemia of the newborn; however, there is still preparation variability among centers.

• Case report: HDFN-associated liver dysfunction treated with chelation therapy

  In a recent case report, an infant with HDFN-associated liver dysfunction experienced positive results when treated with chelation therapy.

• J&J inks deal to utilize UNITY fetal antigen test in phase 3 nipocalimab trial

  The UNITY fetal antigen test will be used to test patients included in the phase 3 AZALEA clinical trial testing nipocalimab to treat HDFN.

• Case report: Severe case of HDFN results in infant death

  The report details a severe case of hemolytic disease of the fetus and newborn (HDFN) that resulted in infant death 10 days after birth.

• Researchers call for increased use of RHIG in China to treat HDFN

  RHIG has been a therapeutic alternative for HDFN for over 50 years, but it isn’t widely used in China due to limited availability.

• Study shows simple blood test could accurately detect HDFN-induced jaundice

  A few predictors easily measured through blood tests appear to accurately distinguish HDFN jaundice from other causes in newborns, according to a study.

• Infants with HDFN at greater risk of iron overload, study shows

  Iron overload during the first three months of life may be a common problem in infants that receive multiple blood transfusions for HDFN.

• Darbepoetin alfa: A potential treatment alternative for HDFN

  According to a study, treatment with darbepoetin alfa appears to reduce transfusion requirements for patients with HDFN.

• Understanding G6PDD: A differential diagnosis to HDFN

  G6PDD is a frequent cause of neonatal jaundice and could represent an important differential diagnosis for HDFN when it is present.

• Case study: Plasmapheresis effective in HDFN patient

  According to a case study, plasmapheresis, a procedure that separates plasma from blood cells, appears to be linked with good outcomes in pregnancies at risk of HDFN.